The enzyme lipase breaks down triglycerides in the small intestine. The blood lipase level does not differ between men and women. In cases of acute pancreatic inflammation, the lipase level in the blood increases within 4–8 hours, peaks at 24 hours, and begins to decrease after 14 days.
Lipase testing for pancreatic diseases is more sensitive and specific compared to amylase. Simultaneous measurement of lipase and amylase allows pancreatic damage to be identified with 98% accuracy
- Blood sample is taken from a vein.
- The test should be performed after 8–14 hours of fasting.
- The test can be taken 4 hours after a light meal.
- Avoid physical and emotional stress, as well as alcohol consumption, prior to the test.
- Acute pancreatitis
- Perforated gastric ulcer
- Chronic pancreatitis
- Acute cholecystitis
- Small bowel obstruction
- Acute and chronic renal failure
- Alcoholism
- Diabetic ketoacidosis
- Liver cirrhosis
- Organ transplantation
- Acute pancreatitis
- Pancreatic tumors
- Intrahepatic cholestasis
- Intestinal infarction
- Pancreatic cyst or pseudocyst
- Peritonitis
- Metabolic disorders (particularly lipid metabolism disorders)
- Epidemic mumps affecting the pancreas