Examinations
Examinations
D-dimer is a marker of thrombosis and fibrinolysis.
Elevated D-dimer levels are observed in various conditions associated with blood coagulation activation, such as disseminated intravascular coagulation (DIC), deep vein thrombosis, pulmonary embolism, massive tissue injuries or surgical procedures, heart failure, infections, inflammatory processes, tumor-related conditions, and more.
D-dimer concentration in the blood is influenced by increased thrombosis, the use of anticoagulants, and thrombolytic therapy, which can raise D-dimer levels.
In pregnant women, D-dimer levels begin to rise steadily from the early months of pregnancy. Significant increases are noted in pregnancy complications (e.g., preeclampsia), as well as in pregnant women with diabetes mellitus or kidney diseases.
It is recommended to have the blood test in the morning on an empty stomach, 8–14 hours after dinner (water is allowed) or 4 hours after a light meal. The day before the blood draw, it is important to reduce psycho-emotional and physical stress and avoid alcohol consumption.
- Diagnosis of thrombotic conditions
- Deep vein thrombosis
- Pulmonary embolism
- Disseminated intravascular coagulation (DIC)
- Pregnancy complications
- Monitoring of thrombolytic therapy.
- Arterial and venous thrombosis (including deep vein thrombosis, pulmonary embolism)
- Disseminated intravascular coagulation (DIC)
- Infection, sepsis
- Inflammation
- Liver disease
- Extensive hematoma
- Pregnancy
- Surgical intervention
- Age over 80 years
- Oncological diseases
- Thrombolytic therapy.