Examinations
Examinations
Prothrombin is a clotting factor secreted by the liver that plays a key role in blood coagulation.
When bleeding occurs, prothrombin is converted into thrombin. Thrombin then converts fibrinogen into fibrin, which forms a clot to stop the bleeding.
The Prothrombin Time (PT) test evaluates fibrinogen, prothrombin, Factor V, Factor VII, and Factor X, which are all essential components of the clotting process.
- It is recommended to give blood in the morning, 8–14 hours after dinner, on an empty stomach (water is allowed), or 4 hours after a light meal in the afternoon.
- Avoid increased psycho-emotional and physical stress (e.g., exercise) and alcohol consumption before the test.
- Screening examination of the blood coagulation system
- Pathological examination of blood coagulation
- Screening of blood coagulation factor reactions
Elevated PT (Prothrombin Time):
- Severe liver diseases
- Vitamin K deficiency
- Conditions causing prolonged bile duct obstruction
- Use of antibiotics
- Disseminated intravascular coagulation (DIC)
- In cases of high PT levels, excessive blood transfusion may be required.
Decreased PT (Prothrombin Time):
- Intake of vitamin K
- Use of estrogen-containing medications, such as oral contraceptives
- Transfusion of fresh frozen plasma.