Nechiporenko Urine Test

12 Azn

According to Dr. Nechiporenko, this urine test allows for more accurate quantification of red blood cells, white blood cells, and casts than a standard urinalysis. Both tests involve microscopy, but the Nechiporenko test counts elements per unit of urine volume, rather than per visual field.

Normally, the kidney glomeruli do not allow blood cells or albumin to pass through. However, certain kidney conditions can damage the filtration barrier, altering the urine composition.
A high red blood cell count in urine (hematuria) may indicate glomerular damage.
Importantly, red blood cells can also be present in urine due to damage, stones, inflammation, or tumors anywhere along the urinary tract — from the renal pelvis to the urethra. However, the presence of red blood cell casts or dysmorphic red blood cells indicates renal origin of hematuria.

  • Avoid spicy, salty foods and foods that may alter urine color (e.g., beets, carrots) 12 hours before the test.

  • Diuretics should be discontinued 48 hours prior to the test (if approved by a physician).

  • Prolonged urinary symptoms (changes in color, smell, clarity, volume, frequency; lower back pain or pain during urination)

  • Suspicious findings or abnormalities in a general urinalysis

  • Systemic diseases with a high risk of kidney involvement

  • During routine health check-ups

  • To monitor treatment effectiveness for urinary tract conditions

Causes of Elevated Values

Red Blood Cells (Hematuria)

  • Renal infarction

  • Glomerulonephritis

  • Urolithiasis

  • Hemorrhagic cystitis

  • Tubulointerstitial nephritis

  • Polycystic kidney disease

  • Severe pyelonephritis

  • Renal trauma

  • Renal tuberculosis

  • Kidney tumor

  • Renal vein thrombosis

  • Benign familial hematuria

  • Benign prostatic hyperplasia

  • Hemophilia

  • Chronic heart failure

  • Subacute infective endocarditis

  • Systemic lupus erythematosus (SLE)

  • Urinary tract infection

  • Leukemia, thrombocytopenia

  • Vasculitis

  • Collagen disorders

  • Goodpasture’s syndrome

  • Malignant hypertension

  • Scurvy (Vitamin C deficiency)

White Blood Cells (Leukocyturia)

  • Acute pyelonephritis

  • Cystitis

  • Glomerulonephritis

  • Nephrotic syndrome

  • Renal tuberculosis

  • Systemic lupus erythematosus

  • Bladder tumor

  • Appendicitis

  • Acute pancreatitis

  • Fever

Epithelial Cells

  • Acute tubular necrosis (e.g., renal infarction)

  • Eclampsia

  • Glomerulonephritis

  • Heavy metal poisoning

  • Tubulointerstitial nephritis

     

    Urinary Casts

    Hyaline Casts

  • Nephrotic syndrome and proteinuria

  • Pyelonephritis

  • Intense physical activity

  • Chronic kidney disease

  • Waxy Casts

  • Chronic kidney disease

  • Diabetic nephropathy

  • Renal amyloidosis

  • Malignant hypertension

  • Kidney transplant rejection

  • Nephrotic syndrome

  • Lipoid nephrosis

  • Paraproteinuria in multiple myeloma

  • Granular Casts

  • Acute kidney injury

  • Chronic mercury poisoning

  • Chronic kidney disease

  • Glomerulonephritis

  • Malignant hypertension

  • Pyelonephritis

  • Renal tuberculosis

  • Pregnancy toxicosis

  • Intense physical stress

  •  
  • Glomerulonephritis

  • Chronic heart failure

  • Diabetic nephropathy

  • Malignant hypertension

  • Dehydration, fever with overheating

  • Emotional stress