IgE (Total)

20 Azn

Immunoglobulin E – an antibody responsible for allergic reactions. Total IgE is primarily synthesized in mucosal tissues, such as the skin, respiratory tract, gastrointestinal tract, tonsils, and others. The amount of IgE in the blood is usually very low.

When an allergen enters the body, it interacts with IgE, forming IgE-specific antigenic complexes. Allergic reactions manifest as rhinitis, bronchitis, asthma, rashes, and in severe cases, anaphylactic shock.

  • The test is performed on a blood sample drawn from a vein.
  • The test can be taken 4 hours after the last light meal.
  • Not recommended to take the test while using glucocorticoids.
  • Antihistamines do not affect the result.
  • Allergic diseases – bronchial asthma, pollinosis, atopic dermatitis, eczema, food and drug allergies.
  • Helminthiasis
  • Assessment of allergy risk in children with a family history of allergies.

Increased IgE Levels (Allergic Diseases):

  • Bronchial asthma
  • Asthmatic bronchitis
  • Pollinosis (hay fever)
  • Urticaria (hives)
  • Atopic dermatitis
  • Quincke’s edema (angioedema)
  • Anaphylactic shock
  • Serum sickness
  • Lyell’s syndrome
  • Stevens-Johnson syndrome
  • Drug allergies
  • Food allergies

Other Causes of Elevated IgE:

  • Wiskott-Aldrich syndrome
  • IgE myeloma
  • Helminth infections
  • Parasitic infections
  • Hyperimmunoglobulin E syndrome