Total Cholesterol

16 Azn

General Information:
Total cholesterol is a crucial marker of lipid metabolism and is used to assess cardiovascular diseases and their complications. About 80% of total cholesterol is synthesized in the body, while the remaining 20% comes from dietary sources. Cholesterol exists in different fractions, such as LDL (Low-Density Lipoproteins), HDL (High-Density Lipoproteins), and VLDL (Very-Low-Density Lipoproteins).

Cholesterol levels are influenced by age and gender. Sex hormones also affect cholesterol levels: estrogens lower cholesterol, while androgens increase it. Physiological increases in cholesterol are observed during pregnancy.

Measuring cholesterol helps determine the risk of atherosclerosis and identify lipid metabolism disorders. High cholesterol levels are associated with an increased risk of coronary heart disease. Cholesterol levels, along with the patient's medical history and lifestyle, are used to calculate the risk of heart attacks and strokes. Measuring cholesterol alongside triglycerides, HDL, LDL, and the atherogenic index provides a more detailed assessment of a patient's condition

  • A venous blood sample is required.
  • Fasting for 8–14 hours before the test is necessary.
  • Avoid physical and emotional stress, as well as alcohol consumption, before the test.
  • Diagnosis of dyslipidemia.
  • Liver and kidney diseases.
  • Endocrine disorders (e.g., hypothyroidism, diabetes).
  • Routine check-ups.
  • Assessment of atherosclerosis risk and related cardiovascular diseases.

Elevated Cholesterol Levels:

  • Genetic predisposition (familial hypercholesterolemia).
  • Excessive intake of animal fats.
  • Diabetes and high blood pressure.
  • Smoking.
  • Overweight/obesity.
  • Excessive alcohol consumption.
  • Liver and kidney diseases.
  • Hypothyroidism.

Decreased Cholesterol Levels:

  • Genetic factors.
  • Severe liver diseases.
  • Bone marrow cancer.
  • Hyperthyroidism.
  • Intestinal malabsorption.
  • Folate or vitamin B12 deficiency anemia.
  • Extensive burns.
  • Tuberculosis.
  • Acute infections.
  • Chronic obstructive pulmonary disease (COPD).