Examinations
Examinations
Fibrinogen forms the basis of a blood clot during coagulation. It is a glycoprotein with a molecular weight of approximately 340,000 Da and is included in the coagulation profile (coagulogram). According to international nomenclature, fibrinogen I (first) constitutes the plasma coagulation system. Fibrinogen is synthesized in the liver.
Physiologically, an increase in fibrinogen levels is observed during pregnancy.
It is recommended to collect blood in the morning, on an empty stomach (water is allowed), 8–14 hours after the evening meal or 4 hours after consuming a light snack.
During the preparation for the test, avoid increased physical activity (such as exercise), psycho-emotional stress, and the consumption of alcoholic beverages.
- Blood clotting disorders
- Preoperative examination
- Examination during pregnancy
- Cardiovascular diseases
- Inflammatory processes
- Acute inflammatory diseases and infections (e.g., flu, tuberculosis)
- Stroke (1st day)
- Pregnancy
- Hypothyroidism
- Myocardial infarction
- Burns
- Amyloidosis
- Malignant tumors
- Use of estrogens and oral contraceptives
Decrease in Fibrinogen Levels:
- Liver disease
- Disseminated intravascular coagulation (DIC)
- Afibrinogenemia
- Vitamin C and B12 deficiencies
- Pregnancy-related toxicosis
- Amniotic fluid embolism in newborns
- Snake venom poisoning
- Chronic myelogenous leukemia
- Polycythemia
- Use of anabolic hormones, androgens, fish oil, valproic acid, and anticoagulants (e.g., streptokinase, urokinase)